MTHFD2 antibody [N1C3] - 25 µL
Alternate_Names : methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase , NMDMC
Applications : ICC | IF | IHC-P | IP | WB
Species_reactivity : Hu Storage_Buffer : PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300. Concentration : 0.13 mg/ml
Form : methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase , NMDMC References : This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement f or magnesium and inorganic phosphate.
Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chrom osome 7. [provided by RefSeq]